Pathology Handbook

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Laboratory:

Clinical Biochemistry

Test Code:

TAC

Medicare rebatable:

Yes

Specimen Types:

Blood

Container Types:

EDTA 3 mL

Adults Volume or Mass:

3 mL

Collection & Request Instructions:

Collect pre-dose
Retrospective testing within 7 days
A separate container is required for this test.

Dedicated tube.

Transport Instructions:

Room Temperature

Assay Frequency:

Daily

External Laboratory:

The Alfred Pathology Service (APS)

External Transport Instructions:

Send at 4'C with Ice Pack

Method:

LCMSMS from 08 January 2010

Additional Notes:

Therapeutic Ranges (pre-dose):

Heart Transplantation

Levels < 6 months post-transplant: 10 - 15 ug/L

Levels >/= 6 months post-transplant: 5 - 10 ug/L

LungTransplantation

Levels < 12 months post-transplant: 9 - 14 ug/L

Levels >/= 12 months post-transplant: 7 - 10 ug/L

Bone Marrow Transplantation
Levels post-transplant: 5—10 ug/L

Renal Transplantation - Trough levels

(in high risk patients, higher levels may be targeted

on discussion with renal consultant)

Levels < 3 months post-transplant: 5 - 10 ug/L

Levels 3 - 6 months post-transplant: 4 - 8 ug/L

Levels > 6 months post-transplant: 4 - 6 ug/L

Method: LCMSMS from 08 January 2010

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