Collect samples Pre Dose
Do not use tubes with gel separator.
Assay run 3 x weekly (Monday, Tuesday & Thursday) - samples must be in the Alfred laboratory by 11AM on each of those day. Results available the following day.
Therapeutic Ranges for Posaconazole
We suggest to monitor Posaconazole trough concentration at steady state (7 days after starting therapy). Levels ≥ 0.7 mg/L are required for prophylaxis and ≥ 1mg/L for invasive fungal infection.
See also POSACONAZOLE DOSING AND THERAPEUTIC DRUG MONITORING
Reference Interval Source:
Chau M, Kong D, van Hal J et al. Consensus guidelines for optimising antifungal drug delivery and monitoring to avoid toxicity and improve outcomes in patients with haematological malignancy, 2014. Internal Medicine Journal 2014; 1364-1388.