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Itraconazole (Sendaway Test)

Laboratory:Clinical Biochemistry
Test Code:ITZ
Medicare rebatable:Yes
Specimen Types:Plasma
Container Types:
EDTA 3 mLEDTA 3 mL
Adults Volume or Mass:3 mL
Collection & Request Instructions:

Collect samples pre dose.

Do not use tubes with gel separator.

Dose information should be provided and length of therapy must be >5 days.

Transport Instructions:Room Temperature
Processing Instructions:Centrifuge
Aliquot
Freeze Immediately
Assay Frequency:3 x weekly (thrice)
External Laboratory:The Alfred Pathology Service (APS)
  External Laboratory details...
Method:

LCMSMS

Additional Notes:

Reference Interval:

Itraconazole (trough) - Localised infection > 0.5 mg/L
                               - Systemic infection >1.0 mg/L

OH-Itraconazole has similar activity to itraconazole and levels can be added to give the sum of both levels ( in this case therapeutic range recommend > 1.0 mg/L).