Pathology Handbook

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Cobalt Plasma (Sendaway Test)

Laboratory:

Clinical Biochemistry

Test Code:

CPL

Medicare rebatable:

Yes

Specimen Types:

Plasma

Container Types:

Metal-Free EDTA

Adults Volume or Mass:

6 mL

Transport Instructions:

Room Temperature

Processing Instructions:

Centrifuge
Aliquot
Store at -20'C

Assay Frequency:

Weekly

External Laboratory:

The Alfred Pathology Service (APS)

External Laboratory details...

External Transport Instructions:

Send at 4'C with Ice Pack

Method:

ICPMS

Additional Notes:

Reference Interval: 2 - 7 nmol/L

Prosthesis wear is known to result in increased circulating concentration of metal ions. Modest increase (68-170nmol/L) in serum cobalt concentration is likely to be associated with a prosthetic device in good condition. Serum concentrations >170nmol/L in a patient with cobalt based implant suggest significant prosthesis wear. Increased serum trace element concentrations in the absence of corroborating clinical information do not independently predict prothesis wear or failure (Source: Mayo Clinic Accessed 22/9/15)

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