Pathology Handbook

Maternal Serum Screening (Sendaway Test)

Alternative Names:

Combined First Trimester Screening (CFTS)
Second Trimester Maternal Serum Screening (2TMSS)
PAPPA-A; free beta hCG
alpha-feto protein; unconjugated estriol; free beta hCG; dimeric inhibin A
Screening for Down syndrome (trisomy 21)
Screening for Edwards syndrome (trisomy 18)
Screening for Patau syndrome (trisomy 13)

Laboratory:

Clinical Biochemistry

Test Code:

MLS

Medicare rebatable:

Yes

Registration Instructions:

Combined First Trimester Screening (CFTS) includes PAPP-A and free beta hCG

Second Trimester Maternal Serum Screening (2TMSS) includes alpha-feto protein, unconjugated estriol, free beta hCG, dimeric inhibin A

Specimen Types:

Serum

Container Types:

SST

Adults Volume or Mass:

5 mL

Collection & Request Instructions:

Combined First Trimester Screening (CFTS) is performed between 9+0 and 13+6 weeks gestation

Second Trimester Maternal Serum Screening (2TMSS) is performed between 14+0 and 20+6 weeks gestation

Refer to MSSO-234_TRF_v5 (vcgs.org.au) for clinical notes/information required by reference laboratory (VCGS)

Transport Instructions:

Room Temperature

Processing Instructions:

Centrifuge

External Laboratory:

Victorian Clinical Genetics Service

External Laboratory details...

External Transport Instructions:

Send at 4'C with Ice Pack

USEFUL LINKS

Frozen Section Booking Form