Pathology Handbook

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Factor V Leiden

Alternative Names:

Factor V Gene Mutation

Laboratory:

Haematology

Test Code:

FVV

Medicare rebatable:

Yes

Registration Instructions:

Can be requested in combination with Prothrombin 20210 Gene Mutation. Only one tube is required for this combination.

Specimen Types:

Blood

Container Types:

EDTA 4 mL

Adults Volume or Mass:

4 mL

Minimum/Paediatric Volume or Mass:

3 mL

Collection & Request Instructions:

For identification of carriers of inherited venous thrombophilia. General population screening and routine screening before prescribing oral contraceptives or hormone replacement therapy are not recommended. test should only be requested by a practioner skilled in genetic counselling of thrombophilia. The significance of a polymorphism in an affected individual is uncertain. Test is Factor -V-Leiden G1691A or R506Q.

PCR assay for detection of Factor V nucleotide substitution causing Activated Protein C Resistance.

Transport Instructions:

Room Temperature

Processing Instructions:

Do Not Centrifuge
Store at Room Temperature

Assay Frequency:

Weekly

USEFUL LINKS

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