Pathology Handbook

Preferred Container Type

Lithium Heparin (without Gel) and Serum (no gel)

Lithium Heparin (without gel), Lithium Heparin Microtainer, Serum (no gel)

Preferred Container Type

Serum - no gel

Lithium Heparin (without Gel) and Serum (no gel)

Frequency

Weekly

Preferred Container Type

Sodium Citrate

Sodium Citrate x 2

Collection & Request Instructions

Collect 2 (TWO tubes). 

Note, as this test is not covered by Medicare, non-Northern Health patients will be responsible for the cost incurred, and patient consent must be obtained.   

Collect 2 (TWO tubes). 

Note, as this test is not covered by Medicare, non-Northern Health patients will be responsible for the cost incurred, and patient consent must be obtained.   

Frequency

Weekdays

Notes

Must be approved by Haematologist and determined very clearly if this test is URGENT or only for batch testing. FBE often have the urgent STICKER attached and this does NOT mean the ADAMTS-13 IS URGENT - CHECK WITH HAEMATOLOGIST/ REGISTRARS

Must be approved by Haematologist and determined very clearly if this test is URGENT or only for batch testing. FBE often have the urgent STICKER attached and this does NOT mean the ADAMTS-13 IS URGENT - CHECK WITH HAEMATOLOGIST/ REGISTRARS.

Urgent same day testing is available when requested and samples reach Monash Health Pathology by 1pm. Please phone the Special Coagulation lab on 9594 6751 if urgent results are required.

Frequency

Weekly

Frequency

Weekly

Alternative names

Jack Jumper Ant allergen

Alternative names

Plane tree allergen, Plane Tree (MAPLE)

Plane tree allergen, London Plane Tree

Collection & Request Instructions

Only 4 allergens / mixes can be requested at any one time. For requests of more than 4 allergens patients will be billed for the excess number.

Minimum volume required 1 mL serum. For multiple allergens add at least 200ul per allergen tested.

Only 4 allergens / mixes can be requested at any one time. For requests of more than 4 allergens patients will be billed for the excess number.

Minimum volume required 1 mL serum. For multiple allergens add at least 200ul per allergen tested.

External Laboratory

Austin Pathology

Dorevitch Pathology

Frequency

Weekly

Collection & Request Instructions

Test cost $240

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Preferred Container Type

Lithium Heparin (without Gel) and Serum (no gel)

Lithium Heparin (without gel), Lithium Heparin Microtainer, Serum (no gel)

Preferred Container Type

Plain tube- serum (No Gel)

Lithium Heparin (without Gel) and Serum (no gel)

Frequency

Weekly

Collection & Request Instructions

Test cost $240

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Collection & Request Instructions

Test cost $240

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Registration Instructions

Requires approval from Director of Pathology.

Requesting clinician also needs to complete a specific request form for the external laboratory: 

https://www.ouh.nhs.uk/immunology/diagnostic-tests/documents/request-card.pdf

Requires approval from Director of Pathology.

A specific request form for the testing laboratory must be completed by the requesting doctor to accompany the specimen: https://www.ouh.nhs.uk/immunology/diagnostic-tests/tests-catalogue/clustered-achr.aspx 

Collection & Request Instructions

Requesting clinician needs to complete a specific request form for the external laboratory: https://www.ouh.nhs.uk/immunology/documents/request-card.pdf and send it together with the request form.

A specific request form for the testing laboratory must be completed by the requesting doctor to accompany the specimen: https://www.ouh.nhs.uk/immunology/diagnostic-tests/tests-catalogue/clustered-achr.aspx 

Frequency

Weekly

Registration Instructions

Turnaround test time approximately 4 weeks. 

Turnaround test time approximately 4 weeks. 

Brain Autoimmunity Laboratory closed from 20/12/2025 to 6/1/2026

Processing Instructions

Centrifuge

Centrifuge
Aliquot
Store at -20'C

External Transport Instructions

Send at 4'C with Ice Pack

Send Frozen on Dry Ice

External Laboratory

The Children's Hospital at Westmead

Kids Neuroscience Centre

Registration Instructions

All specimens from 18/12/2024 to 05/01/2024 are to be frozen and sent to the referral laboratory from 06/01/2024

Turnaround test time approximately 4 weeks. 

Turnaround test time approximately 4 weeks. 

Request Group

ASK

SKE

Alternative names

Autoimmune Encephalopathy Testing

Autoimmune Encephalopathy Testing, NMDA, CASPR2, LG1, AMPA, GABAB, DPPX

Preferred Container Type

SST
CSF Tube 1

SST
CSF Tube 3

Request Group

MND

AES (serum) , AEC (CSF)

Collection & Request Instructions

CSF volume: 1 mL 

Test cost $240

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

CSF volume: 1 mL 

Laboratory

Haematology

Genetics

Registration Instructions

This requst must be approved by the Director of Pathology prior to sending. 

Collection & Request Instructions

Contact the laboratory prior to collection to determine the best day to collect the specimen.  This requst must be approved by the haematology registrar prior to sending

Contact the laboratory prior to collection to determine the best day to collect the specimen. 

External Transport Instructions

This requst must be approved by the haematology registrar prior to sending

This requst must be approved by the Director of Pathology prior to sending

Frequency

Daily

Preferred Specimen Type

Blood

Blood
Bone Marrow

Registration Instructions

Requires approval from Laboratory Haematology registrar or consultant. 

Calreticulin is no longer available as a single gene mutation testing. It is now tested as part of the MPN NGS panel - clinicians should request for MPN NGS instead.

Requires approval from Laboratory Haematology registrar or consultant. 

Calreticulin is no longer available as a single gene mutation testing. It is now tested as part of the MPN NGS panel - clinicians should request for MPN NGS instead.

Calreticulin testing only available as part of either All Haem DNA (80gene) or MPN (22 gene) assay.

AllHaem DNA $825.50 (MBS rebateable); MPN panel $475 (MBS rebateable for certain indications)

External Transport Instructions

Send at 4'C with Ice Pack

Send at ambient temperature

External Transport Instructions

Send at 4'C with Ice Pack

Send at ambient temperature

Assay name

Chlamydia and Gonorrhoea PCR (Eye, Anorectal, Throat/Pharyngeal)

Chlamydia and Gonorrhoea PCR (Eye)

Registration Instructions

This panel is only to be used for eye, anorectal, throat, pharyngeal swabs.  

This panel is only to be used for eye swabs.  

Assay name

Chlamydia and Gonorrhoea PCR (Urine, Vaginal, Cervical, Urethral)

Chlamydia and Gonorrhoea PCR (Urine, Vaginal, Cervical, Urethral, Anorectal, Throat/Pharyngeal)

Registration Instructions

Copan swabs and urine only. 

If Cobas swab is received, please panel UCG (Alfred)

If eye swab / Anorectal / Throat (pharyngeal) is received, please panel CTN (VIDRL)

Copan swabs and urine only. 

If Cobas swab is received, please panel UCG (Alfred)

If eye swab is received, please panel CTN (VIDRL)

Collection & Request Instructions

1 x LH or Salivary Kit

• Karyotype/Chromosomes/G-banded Karyotype = 1 x 6mL LH

• Salivary Kit may be obtained from pathology.

1 x Litihum Heparin 

• Karyotype/Chromosomes/G-banded Karyotype = 1 x 6mL Lithium Heparin 

Registration Instructions

External request does not require approval. 

Approved indications for Northern Health patients:

• Requested by Paediatrician and clinical notes indicate developmental delay
• Pregnancy loss

Otherwise seek approval from the Director of Pathology prior to sending. 

External request does not require approval. 

Approved indications for Northern Health patients:

• Requested by Paediatrician and clinical notes indicate developmental delay
• Pregnancy loss
• Requested by Northern Health Fertility clinic

Otherwise seek approval from the Director of Pathology prior to sending. 

External Transport Instructions

External request does not require approval. 

Approved indications for Northern Health patients:

• Requested by Paediatrician and clinical notes indicate developmental delay
• Pregnancy loss

Otherwise seek approval from the Director of Pathology prior to sending. 

External request does not require approval. 

Approved indications for Northern Health patients:

• Requested by Paediatrician and clinical notes indicate developmental delay
• Pregnancy loss
• Requested by Northern Health Fertility clinic

Otherwise seek approval from the Director of Pathology prior to sending. 

Collection & Request Instructions

Indicate whether the patient is immunosuppressed in the clinical notes.

Assay name

Cryptococcal Antigen Serum (Sendaway Test)

Cryptococcal Antigen

Request Group

CRA

CTA

Preferred Specimen Type

Serum

Serum
Cerebrospinal Fluid

Preferred Container Type

SST

SST
CSF Tube 3

External Laboratory

The Alfred Pathology Service (APS)

External Transport Instructions

Send at 4'C with Ice Pack

Frequency

Weekdays

Daily

Frequency

Weekly

Laboratory

Haematology

Immunology

Volume (Adults)

3 mL

0.5 mL

Minimum/Paediatric Volume

0.1 mL

Registration Instructions

This is a non-MBS test. Test cost is $150.

Collection & Request Instructions

Do not collect on a Friday as Friday samples MUST reach the external laboratory by 1pm.

Collect Monday - Thursday at any time.  Do not collect on a Friday as Friday samples MUST reach the external laboratory by 1pm.

Processing Instructions

Store at 4'C

Store at 4'C
Do Not Centrifuge
Unopened Tube

Alternative names

Influenza A/B PCR, RSV PCR, Flu virus PCR, Respiratory virus extended panel, parainfluenza PCR, human metapneumovirus PCR, adenovirus PCR, Rhinovirus PCR, SAR

Influenza A/B PCR, RSV PCR, Flu virus PCR, Respiratory virus extended panel, parainfluenza PCR, human metapneumovirus PCR, adenovirus PCR, Rhinovirus PCR, SAR, Respiratory virus PCR

Alternative names

Influenza A/B PCR, RSV PCR, Flu virus PCR, Respiratory virus extended panel, parainfluenza PCR, human metapneumovirus PCR, adenovirus PCR, Rhinovirus PCR

Influenza A/B PCR, RSV PCR, Flu virus PCR, Respiratory virus extended panel, parainfluenza PCR, human metapneumovirus PCR, adenovirus PCR, Rhinovirus PCR, SAR

Registration Instructions

Test performed fortnightly. Phone the Monash Special Coagulation lab if urgent results are required - 9594 6751 

Frequency

Fortnightly

Transport Instructions between sites and/or laboratories

On Ice
Send to lab immediately

Room Temperature

Processing Instructions

Time critical - do not delay handling !

Centrifuge
Aliquot

External Transport Instructions

Send at 4'C with Ice Pack

Send Frozen on Dry Ice

Collection & Request Instructions

This test has poor specificity and has been discontinued.  For investigation of fat malabsorption please consider faecal elestase.  Not to be confused with Faecal Fat (72hrs).

This test has poor specificity and has been discontinued.  

Collection & Request Instructions

This test has poor specificity and has been discontinued.  For investigation of fat malabsorption please consider faecal elestase.  Not to be confused with Faecal Fat (72hrs).

Frequency

Daily

Alternative names

Group B Arbovirus PCR

Group B Arbovirus PCR, Dengue PCR

Request Group

FLA

TNA

Registration Instructions

Use if a Flavivirus screen is requested or if agent specified does not have a test code.

Individual tests need to be requested (Japanese B encephalitis serology, Kunjin virus serology, Murray Valley encephalitis serology).  Contact the requesting doctor to confirm what tests are required.   

Collection & Request Instructions

Please specify agents required along with relevant travel/exposure history.

Please specify agents required along with relevant travel/exposure history.

Collection & Request Instructions

Test cost $240

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Registration Instructions

CSF sample should be directed to Microbiology (NPV) prior to forwarding to refer laboratory.

Test cost $240

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Can be ordered in combination with NMDA, AMPA, ANTI- LGI 1, ANTI- CASPR2, ANTI DPX, ANTI- VGKC. (1.0ml csf is adequate for combination testing).

　

Samples suitable for auto-antibody screening:

Blood Serum: request for 5.0 mls of blood collected in serum gel with tubes (SST)

CSF: request for 1.0mls

Samples not available for delivery following collection are to be stored at 4oC and delivered on ice. Storage at 4oC is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

Urgent requests can be performed on receival by refering laboratory.

CSF sample should be directed to Microbiology (NPV) prior to forwarding to refer laboratory.

Test cost $240

For non Northern Health patients the attached billing consent form must be completed:

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Can be ordered in combination with NMDA, AMPA, ANTI- LGI 1, ANTI- CASPR2, ANTI DPX, ANTI- VGKC. (1.0ml csf is adequate for combination testing).

　

Samples suitable for auto-antibody screening:

Blood Serum: request for 5.0 mls of blood collected in serum gel with tubes (SST)

CSF: request for 1.0mls

Samples not available for delivery following collection are to be stored at 4oC and delivered on ice. Storage at 4oC is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

Urgent requests can be performed on receival by refering laboratory.

Registration Instructions

CSF sample should be directed to Microbiology (NPV) prior to forwarding to refer laboratory.

Test cost $240

Can be ordered in combination with NMDA, AMPA, ANTI- LGI 1, ANTI- CASPR2, ANTI DPX, ANTI- VGKC. (1.0ml csf is adequate for combination testing).

　

Samples suitable for auto-antibody screening:

Blood Serum: request for 5.0 mls of blood collected in serum gel with tubes (SST)

CSF: request for 1.0mls

Samples not available for delivery following collection are to be stored at 4oC and delivered on ice. Storage at 4oC is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

Urgent requests can be performed on receival by refering laboratory.

CSF sample should be directed to Microbiology (NPV) prior to forwarding to refer laboratory.

Test cost $240

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Can be ordered in combination with NMDA, AMPA, ANTI- LGI 1, ANTI- CASPR2, ANTI DPX, ANTI- VGKC. (1.0ml csf is adequate for combination testing).

　

Samples suitable for auto-antibody screening:

Blood Serum: request for 5.0 mls of blood collected in serum gel with tubes (SST)

CSF: request for 1.0mls

Samples not available for delivery following collection are to be stored at 4oC and delivered on ice. Storage at 4oC is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

Urgent requests can be performed on receival by refering laboratory.

Registration Instructions

Requires approval from Director of Pathology.

Cost - 50UKP

A specific request form for the testing laboratory must be completed by the requesting doctor to accompany the specimen: https://www.ouh.nhs.uk/immunology/diagnostic-tests/tests-catalogue/clustered-achr.aspx 

Collection & Request Instructions

Test is performed in UK. Requesting clinician needs to complete the Neuroimmunology Request card for the external laboratory: https://www.ouh.nhs.uk/immunology/diagnostic-tests/ordering-tests.aspx 

More information on the test: https://www.ouh.nhs.uk/immunology/diagnostic-tests/tests-catalogue/ganglionic-acetylcholine-receptor-antibodies.aspx 

A specific request form for the testing laboratory must be completed by the requesting doctor to accompany the specimen: https://www.ouh.nhs.uk/immunology/diagnostic-tests/tests-catalogue/clustered-achr.aspx 

More information on the test: https://www.ouh.nhs.uk/immunology/diagnostic-tests/tests-catalogue/ganglionic-acetylcholine-receptor-antibodies.aspx 

Volume (Adults)

6 mL

3 mL

Minimum/Paediatric Volume

0.6 mL

Collection & Request Instructions

Specimen viable for 1 week at 4^oC

Frequency

3 x weekly (thrice)

Assay name

Hepatitis A IgG (Sendaway Test)

Hepatitis A IgG

Request Group

HAG

HAI

Registration Instructions

Unless indicated otherwise on the request form, also register for Hepatitis A IgM (HAM). 

Minimum volume 0.5ml.

Minimum volume 0.5ml.

External Laboratory

The Alfred Pathology Service (APS)

External Transport Instructions

Send at 4'C with Ice Pack

Frequency

Daily

Assay name

Hepatitis A IgM (Sendaway Test)

Hepatitis A IgM

Request Group

HAM

HAI

Registration Instructions

Unless indicated otherwise on the request form, also register for Hepatitis A IgG (HAG)

Minimum serum volume 0.5 ml.

Minimum serum volume 0.5 ml.

External Laboratory

The Alfred Pathology Service (APS)

External Transport Instructions

Send at 4'C with Ice Pack

Frequency

Daily

Request Group

HBE

HEB

Transport Instructions between sites and/or laboratories

Store at 4C

Room Temperature

External Laboratory

The Alfred Pathology Service (APS)

V.I.D.R.L.

External Transport Instructions

Send at 4'C with Ice Pack

Request Group

BEA

HET

External Laboratory

The Alfred Pathology Service (APS)

V.I.D.R.L.

Frequency

Weekly

Request Group

HBS

HBM

External Laboratory

The Alfred Pathology Service (APS)

V.I.D.R.L.

External Transport Instructions

Send at ambient temperature

Send at 4'C with Ice Pack

External Transport Instructions

Should only be sent if the patient has travelled overseas

Assay name

Herpes Virus Multiplex PCR (Sendaway Test)

Herpes Virus Multiplex PCR ( BAL and Urine)(Sendaway Test)

Registration Instructions

Swabs and plasma specimens panel MNV (inhouse)

Tissue specimens not accepted for testing and need to order HSP (VIDRL)

Preferred Specimen Type

Plasma
Tissue
Swab

Bronchoalveolar Lavage
Urine random

Collection & Request Instructions

Tissue specimens not accepted for testing and need to order HSP (VIDRL)

For quantitative CMV PCR order CMV Viral Load.

A separate EDTA blood tube is essential. It cannot be used for other tests. 4 ml EDTA is acceptable if full.

For investigation of CMV colitis, a colonic biopsy is recommended. For all other enquires, please contact the Microbiology Registrar.

Tissue specimens not accepted for testing and need to order HSP (VIDRL)

For quantitative CMV PCR order CMV Viral Load.

For investigation of CMV colitis, a colonic biopsy is recommended. For all other enquires, please contact the Microbiology Registrar.

Registration Instructions

A separate EDTA blood tube is essential.  It cannot be used for other tests. 4 ml EDTA is acceptable if full.

A separate EDTA blood tube is essential.  It cannot be used for other tests. 4 ml EDTA is acceptable if full.  EDTA specimens require centrifugation.

Collection & Request Instructions

A separate EDTA blood tube is essential.  It cannot be used for other tests. 4 ml EDTA is acceptable if full.

A separate EDTA blood tube is essential.  It cannot be used for other tests. 4 ml EDTA is acceptable if full.

Processing Instructions

Centrifuge

Assay name

Herpes Virus Multiplex PCR (Swab and plasma)

Herpes Virus Multiplex PCR (Swab, CSF and plasma)

Preferred Container Type

Viral Transport Medium Swab
EDTA 4 mL
EDTA 10 mL

Viral Transport Medium Swab
EDTA 4 mL
EDTA 10 mL
CSF tube

Volume (Adults)

6 mL

4 mL

Registration Instructions

A separate EDTA blood tube is essential.  It cannot be used for other tests. 4 ml EDTA is acceptable if full.

Collection & Request Instructions

A separate EDTA blood tube is essential.  It cannot be used for other tests. 4 ml EDTA is acceptable if full.

Assay name

Herpes Virus Multiplex PCR (Swab)

Herpes Virus Multiplex PCR (Swab and plasma)

Alternative names

HSV 1 PCR, HSV 2 PCR, VZV PCR

HSV 1 PCR, HSV 2 PCR, VZV PCR, CMV PCR

Volume (Adults)

6 mL

Minimum/Paediatric Volume

2.0 mL

Preferred Specimen Type

Swab

Swab
Plasma

Preferred Container Type

Viral Transport Medium Swab

Viral Transport Medium Swab
EDTA 4 mL
EDTA 10 mL

Registration Instructions

HTLV PCR only performed if the serology is positive.  If there is no previous serology, please contact the referring doctor to request for HTLV serology instead.

If HTLV serology has been performed, please contact the Clinical Microbiologist for approval prior to sending the test.  This applies to all patients (both private and public).

Transport Instructions between sites and/or laboratories

For Northern Health patient, seek authorisation from Microbiologist before sending the test.

Send to VIDRL as soon as possible after collection.

For all patients, seek authorisation from Microbiologist before sending the test.

Send to VIDRL as soon as possible after collection.

Registration Instructions

If test is requested please issue comment "Test not available. If testing for Human Herpes 6 virus is clinically indicated, please contact the Clinical Microbiologist to discuss."

Request Group

ITR

ITF

Registration Instructions

Specimens will not be accepted for testing between 23/12/2025 and 04/01/2026.  Specimens are to be aliquoted and kept at 4^oC.

Specimens will not be accepted for testing between 23/12/2025 and 04/01/2026.  Specimens are to be aliquoted and kept at -20^oC.

Registration Instructions

Specimens will not be accepted for testing between 20/12/2023 and 01/01/2024.

Specimens will not be accepted for testing between 23/12/2025 and 04/01/2026.  Specimens are to be aliquoted and kept at 4^oC.

Collection & Request Instructions

Collect Mon-Thurs only for all sites. For Northern Epping site, can collect on Friday (or day before public holidays) until 1pm.

Please provide relevant clinical history and specify exact type of flow cytometric analysis required.

For peripheral blood sample, an FBE must also be requested. Collect 2xEDTA. 

For CSF sample, please collect a tube with 2-3mL RPMI from Central Specimen Reception BEFORE the CSF sample is collected. CSF should be collected directly into this tube (1 part RPMI; 1 part CSF) to improve sample yield. All CSF flow requests must also have CYTOLOGY requested.

Samples must be marked “Urgent”. Flow cytometry is NOT available after 1pm on Fridays or during weekends/afterhours. Testing during these times require approval from a laboratory haematologist PRIOR to sample collection. Otherwise, the sample may not be tested in time (within 2-4 hours for CSF, up to 24 hours for blood sample) or tested at all. Samples not processed in time is non-viable and non-diagnostic. 

Laboratory haematologist can be contacted on 8405 2596 during normal working hours or via switchboard after hours.

Collect Mon-Thurs only for all sites. For Northern Epping site, can collect on Friday (or day before public holidays) until 1pm.

Please provide relevant clinical history and specify exact type of flow cytometric analysis required.

For peripheral blood sample, an FBE must also be requested. Collect 2xEDTA. 

All non-peripheral blood samples must be accompanied by a histology/cytology request. Ensure appropriate and adequate specimens.

For CSF sample, please collect a tube with 2-3mL RPMI from Central Specimen Reception BEFORE the CSF sample is collected. CSF should be collected directly into this tube (1 part RPMI; 1 part CSF) to improve sample yield. All CSF flow requests must also have CYTOLOGY requested.

Samples must be marked “Urgent”. Flow cytometry is NOT available after 1pm on Fridays or during weekends/afterhours. Testing during these times require approval from a laboratory haematologist PRIOR to sample collection. Otherwise, the sample may not be tested in time (within 2-4 hours for CSF, up to 24 hours for blood sample) or tested at all. Samples not processed in time is non-viable and non-diagnostic. 

Laboratory haematologist can be contacted on 8405 2596 during normal working hours or via switchboard after hours.

Collection & Request Instructions

Test cost $240

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Registration Instructions

CSF sample should be directed to Microbiology (NPV) prior to forwarding to refer laboratory.

Test cost $240

Can be ordered in  combination with: NMDA, GABA_{B ,} AMPA, ANTI- CASPR2, ANTI- DPPX. (1.0ml csf is adequate for combination testing).

　

Samples suitable for auto-antibody screening:

Blood Serum: request for 5.0 mls of blood collected in serum gel tube (SST).

CSF: request for 1.0ml

Samples not available for delivery following collection are to be stored at 4^o C. Storage at 4oC is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

CSF sample should be directed to Microbiology (NPV) prior to forwarding to refer laboratory.

Test cost $240

For non Northern Health patients the attched billing consent form must be completed:

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Can be ordered in  combination with: NMDA, GABA_{B ,} AMPA, ANTI- CASPR2, ANTI- DPPX. (1.0ml csf is adequate for combination testing).

　

Samples suitable for auto-antibody screening:

Blood Serum: request for 5.0 mls of blood collected in serum gel tube (SST).

CSF: request for 1.0ml

Samples not available for delivery following collection are to be stored at 4^o C. Storage at 4oC is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

Registration Instructions

Collect from Monday to Thursday only. Test must be requested by a Paediatrician (Consultant).  CSR staff to check with Haematology Registrar prior to sending.  Test must be performed within 48 hours of collection (lithium heparin).

FBE to performed at NPV and results to be send to RCH with the lithium heparin specimen.

CSR staff to check with Haematology Registrar prior to sending.  Test must be performed within 48 hours of collection (lithium heparin).

FBE to performed at NPV and results to be send to RCH with the lithium heparin specimen.

Collection & Request Instructions

Collect from Monday to Thursday only. Test must be requested by a Paediatrician (Consultant). 

Request Group

FLW (for paper request), MBC (for EMR request)

FLW (for paper request), MBH (for EMR request)

Preferred Container Type

EDTA
Lithium Heparin (with Gel)

EDTA
Lithium Heparin (without Gel)

Collection & Request Instructions

A separate container is required for this test.
 

0.5mL Lithium Heparin required and 0.5mL EDTA for an FBE

Flow cytometric analysis is referred to Royal Children's and the test needs to be performed within 24 hours of collection. As the sample will need to be transported to the Royal Children's hospital, only collect the sample on Monday-Thursday. This test is not available on weekends or public holidays.  

A separate container is required for this test.
 

0.5mL Lithium Heparin (without gel) required and 0.5mL EDTA for an FBE

Flow cytometric analysis is referred to Royal Children's and the test needs to be performed within 24 hours of collection. As the sample will need to be transported to the Royal Children's hospital, only collect the sample in the afternoon Monday-Thursday. This test is not available on weekends or public holidays.  

Frequency

Weekly

Frequency

Weekly

Alternative names

Prader -Willi Syndrome, Prader Willi Syndrome, Angelman Syndrome

Prader -Willi Syndrome, Prader Willi Syndrome

Alternative names

Prader -Willi Syndrome, Prader Willi Syndrome

Prader -Willi Syndrome, Prader Willi Syndrome, Angelman Syndrome

Alternative names

Y chromosome microdeletion

Assay name

Mitochondrial Autoantibodies (Send away Test) - Austin

Mitochondrial Autoantibodies (Send away Test) - Austin P

Registration Instructions

Must be transported to the referral laboratory within 72 hours.

Processing Instructions

Do Not Centrifuge

Do Not Centrifuge
Store at Room Temperature

External Transport Instructions

Send at ambient temperature

External Laboratory

Victorian Clinical Genetics Service

PathWest QEII Medical Centre

Collection & Request Instructions

Mycobacterial culture should also be requested

The use of nucleic acid amplification tests (NAAT) for screening specimens from patients with suspected TB should be limited to:

• Respiratory smear-positive specimens where the result is likely to influence clinical (treatment) and/or public health (isolation, contact investigation) decisions;

• Respiratory smear-negative specimens from a patient with a high probability of TB, when prompt management and public health decisions are required; and

• Selected non-respiratory specimens (e.g. meningeal, some tissue biopsies) where a prompt management decision is necessary (recognised that such tests have not been validated or approved).

The use of NAAT is considered inappropriate in the following instances:

• When a patient is respiratory smear-negative and has a low probability of TB;
• When a patient is respiratory smear-positive and has a very high probability of TB;
• Paucibacillary non-respiratory specimens (e.g. pleural fluid, ascitic fluid).

Mycobacterial culture should also be requested

The use of nucleic acid amplification tests (NAAT) for screening specimens from patients with suspected TB should be limited to:

• Respiratory smear-positive specimens where the result is likely to influence clinical (treatment) and/or public health (isolation, contact investigation) decisions;

• Respiratory smear-negative specimens from a patient with a high probability of TB, when prompt management and public health decisions are required; and

• Selected non-respiratory specimens (e.g. meningeal, some tissue biopsies) where a prompt management decision is necessary (recognised that such tests have not been validated or approved).

The use of NAAT is considered inappropriate in the following instances:

• When a patient is respiratory smear-negative and has a low probability of TB;
• When a patient is respiratory smear-positive and has a very high probability of TB;
• Paucibacillary non-respiratory specimens (e.g. pleural fluid, ascitic fluid).

Specimens in RPMI not suitable for testing 

Request Group

MYC

MPG

External Laboratory

The Alfred Pathology Service (APS)

V.I.D.R.L.

Frequency

Weekly

Request Group

FUN

FCU

Processing Instructions

Store at Room Temperature

External Laboratory

The Alfred Pathology Service (APS)

External Transport Instructions

Send at ambient temperature

Alternative names

DHR

Preferred Container Type

ACD and EDTA

ACD

Registration Instructions

CSF sample should be forwarded to Microbiology (NPV) prior to sending to referring laboratory.

Test cost $240

For non Northern Health patients the attached billing consent form must be completed:

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Can be ordered in combination with GABA_B , AMPA, ANTI- LGI 1, ANTI- CASPR2, ANTI- DPPX, ANTI-VGKC(1.0mls csf is adequate for combination testing)

Samples suitable for auto-antibody screening:

Blood Serum: request for 5.0 mls of blood collected in serum gel (SST)

CSF: request for 1.0ml

Storage at 4oC is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

CSF sample should be forwarded to Microbiology (NPV) prior to sending to referring laboratory.

Test cost $269

For non Northern Health patients the attached billing consent form must be completed:

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Can be ordered in combination with GABA_B , AMPA, ANTI- LGI 1, ANTI- CASPR2, ANTI- DPPX (1.0mls csf is adequate for combination testing). If AEC or AES is registered on a sample then NMC and NMD do not need to be registered as AEC/AES includes NMDA testing. 

Samples suitable for auto-antibody screening:

Blood Serum: request for 5.0 mls of blood collected in serum gel (SST)

CSF: request for 1.0ml

Storage at 4oC is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

Collection & Request Instructions

Test cost $240

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Test cost $269

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Laboratory

Molecular

Immunology

Collection & Request Instructions

Test cost $240

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Registration Instructions

CSF sample should be forwarded to Microbiology (NPV) prior to sending to referring laboratory.

Test cost $240

Can be ordered in combination with GABA_B , AMPA, ANTI- LGI 1, ANTI- CASPR2, ANTI- DPPX, ANTI-VGKC(1.0mls csf is adequate for combination testing)

Samples suitable for auto-antibody screening:

Blood Serum: request for 5.0 mls of blood collected in serum gel (SST)

CSF: request for 1.0ml

Storage at 4oC is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

CSF sample should be forwarded to Microbiology (NPV) prior to sending to referring laboratory.

Test cost $240

For non Northern Health patients the attached billing consent form must be completed:

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Can be ordered in combination with GABA_B , AMPA, ANTI- LGI 1, ANTI- CASPR2, ANTI- DPPX, ANTI-VGKC(1.0mls csf is adequate for combination testing)

Samples suitable for auto-antibody screening:

Blood Serum: request for 5.0 mls of blood collected in serum gel (SST)

CSF: request for 1.0ml

Storage at 4oC is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

Frequency

Weekly

Processing Instructions

Unopened Tube

Unopened Tube
Centrifuge

Processing Instructions

Centrifuge

Processing Instructions

Store upto 1 week at 4oC, or freeze (-20oC) if longer

Store upto 1 week at 4^oC, or freeze (-20^oC) if longer

Volume (Adults)

6 mL

2 mL

Minimum/Paediatric Volume

2 mL

Processing Instructions

Centrifuge

Centrifuge
Store at 4'C

Registration Instructions

Non-CMBS test - $42

Non-CMBS test - $42

Test performed fortnightly. Phone the Monash Special Coagulation lab if urgent results are required - 9594 6751.

Frequency

Fortnightly

Collection & Request Instructions

Patients should be provided with the patient information sheet. Collectors, please record patient medication on request slip or the collection staff questionnaire.

This test can only be collected at Northern Pathology Victoria Epping (TNH) collection rooms and performed on Tuesdays and Thursdays (between 9am to 12pm) excluding Public Holidays.

Clinicians to provide patient with Patient information sheet. Patient to contact Laboratory Haematology 8405 8369 to make their appointment.

Do NOT send sample via pneumatic tube. Must be hand delivered to the lab within 1 hour.
Do NOT place on ice - maintain at room temperature. Do NOT centrifuge.

Patients should be provided with the patient information sheet. Collectors, please record patient medication on request slip or the collection staff questionnaire. 

This test can only be collected at Northern Pathology Victoria Epping (TNH) collection rooms only by appointment and performed on Tuesdays and Thursdays (between 9am to 12pm) excluding Public Holidays.

Clinicians to provide patient with Patient information sheet. Patient to contact Laboratory Haematology 8405 8369 to make their appointment.

Do NOT send sample via pneumatic tube. Must be hand delivered to the lab within 1 hour.
Do NOT place on ice - maintain at room temperature. Do NOT centrifuge.

Collection & Request Instructions

Need minimum 9mL of Blood (ie full 10ml EDTA tube) or 1-2mL of Bone Marrow (EDTA).

Specimens must be kept at room temperature and must be less than 24hours old - DO NOT FREEZE. Samples must be received in RPAH lab within 48 hours of collection.

Specimens should be collected on alternate Tuesdays, to be sent to the RPAH lab on the next day Wednesday interstate courier. Liase with the Haematology Registrar before collecting.

Lab reg to email diagnostic report (including PML::RARA breakpoint) and date to SLHD-RPAMolecularHaematology@health.nsw.gov.au

Need minimum 2 x 9mL of Blood (ie full 10ml EDTA tube) or 1-2mL of Bone Marrow (EDTA).

Specimens must be kept at room temperature and must be less than 24hours old - DO NOT FREEZE. Samples must be received in RPAH lab within 48 hours of collection.

Specimens should be collected on alternate Tuesdays, to be sent to the RPAH lab on the next day Wednesday interstate courier. Liase with the Haematology Registrar before collecting.

Lab reg to email diagnostic report (including PML::RARA breakpoint) and date to SLHD-RPAMolecularHaematology@health.nsw.gov.au

Registration Instructions

If test ordered by an immunologist no approval required.

Assay name

QuantiFERON®-TB Kit (Sendaway Test)

QuantiFERON®-TB Kit

Request Group

QTB

QTF

External Laboratory

The Alfred Pathology Service (APS)

External Transport Instructions

Send at 4'C with Ice Pack

Alternative names

T regs

Request Group

RTC

RTC, also requires collection of FBE

Volume (Adults)

4 mL

0.5 mL

Minimum/Paediatric Volume

0.5 mL

Registration Instructions

CSR to organise FBE if not already performed on this collection and send results with Lithium heparin sample to the Royal Children's hospital. 

Preferred Container Type

EDTA 4 mL

Lithium Heparin (without Gel)
EDTA

Collection & Request Instructions

Haemotologist authorisation required. Monday - Thursday only.

A separate container is required for this test.

0.5mL Lithium Heparin (without gel) required and 0.5mL EDTA for an FBE

Flow cytometric analysis is referred to Royal Children's and the test needs to be performed within 24 hours of collection. As the sample will need to be transported to the Royal Children's hospital, only collect the sample Monday-Thursday. This test is not available on weekends or public holidays.  
 

Transport Instructions between sites and/or laboratories

Room Temperature

Room Temperature
Send to lab immediately

Processing Instructions

Store at Room Temperature

Store at Room Temperature
Do Not Centrifuge

External Transport Instructions

Send at ambient temperature

Frequency

Daily

Notes

This assay has a 7 day minimum re-order interval due to limited clinical utility of frequent repeat testing. If you repeat testing is considered clinically necessary, please contact Immunology for guidance or approval.

Registration Instructions

Requires approval from Laboratory Haematology Registrar/Consultant. 

Requires approval from Laboratory Haematology Registrar/Consultant. 

Frequency

Weekly

MBS rebatable

Yes

No

Registration Instructions

If only SCA 15 is requested, sent to VCGS. Refer to SCA 15 entry. 

For Northern Health patients, if not requested by Neurologist or Neurology unit, seek approval from Director of Pathology. All external requests require approval from Director of Pathology. 

If only SCA 15 is requested, sent to VCGS. Refer to SCA 15 entry. 

For Northern Health patients, if not requested by Neurologist or Neurology unit, seek approval from Director of Pathology.

All external requests require approval from Director of Pathology. 

Registration Instructions

If only SCA 15 is requested, sent to VCGS. Refer to SCA 15 entry. 

For Northern Health patients, if not requested by Neurologist or Neurology unit, seek approval from Director of Pathology. All external requests require approval from Director of Pathology. 

Registration Instructions

Criteria to be fulfilled prior to sending the test out:

1. Patients with positive syphilis serology on serum

2. A concurrent serum is available, which is to be sent to VIDRL for parellel testing, along with the CSF.

Please speak with duty Microbiologist if there are any questions.

Criteria to be fulfilled prior to sending the test out:

1. Patients with positive syphilis serology on serum

2. A concurrent serum (must be panelled SYC) is available, which is to be sent to VIDRL for parellel testing, along with the CSF.

Please speak with duty Microbiologist if there are any questions.

Frequency

Weekly

Frequency

As Required

Processing Instructions

Centrifuge twice
Aliquot
Freeze Immediately
Store at -70'C

Centrifuge
Aliquot
Freeze Immediately
Store at -70'C

Processing Instructions

Aliquot
Store at 4'C

Store at -20'C

External Laboratory

Australian Clinical Labs- prev.Healthscope

Sydney South West Path (SSWPS) - Concord

External Laboratory

Austin Pathology

Australian Clinical Labs- prev.Healthscope

Registration Instructions

Haematology registrar / consultant approval must be given prior to dispatch.

6 x Sodium Citrate and 2 x serum (red top no-gel) required

Haematology registrar / consultant approval must be given prior to dispatch.

6 x Sodium Citrate and 2 x serum (red top no-gel) required

Monash Health Pathology can perform PF4 ELISA's with approx. weekly turnaround time. Please label request clearly with VITT to distinguish from HITT requests.

Alternative names

Anti-VGKC.

Anti-VGKC

Volume (Adults)

1 mL

Registration Instructions

CSF sample should be directed to Microbiology (NPV) prior to forwarding to refer laboratory.

Test cost $240

For non Northern Health patients the attached billing consent form must be completed:

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Can be ordered in combination with:  NMDA, GABA_B , AMPA, ANTI- LGI 1, ANTI -CASPR2, ANTI- DPPX. (1.0ML csf is adequate for combination testing).

Blood Serum: request for 5.0 mls of blood collected in serum gel (SST).

CSF: request for 1.0mls

Samples not available for delivery following collection are to the department to book in an to be stored at 4 ^oC. Storage at 4 ^o C is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

Please note: This service is not Medicare rebatable and non Northern Health patients may be charged. Please contact Pathology Queensland for current pricing (07 3646 5811)

Test is only available on Serum.  If requested on CSF register AEC instead. 

Samples not available for delivery following collection are to be stored at 4 ^oC. Storage at 4 ^o C is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

Collection & Request Instructions

Test cost $240

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Associated with Acquired neuromyotonia and Limbic encephalitis-like syndromes.

Please include all the provisional, diagnosis or clinical signs.

Please note: This service is not Medicare rebatable and non Northern Health patients may be charged. Please contact Pathology Queensland for current pricing (07 3646 5811)

Please include all the provisional, diagnosis or clinical signs.

External Laboratory

Mitochondrial and Autoimmune Neurological Disorder

Pathology Queensland- RBWH Campus

External Transport Instructions

Urgent requests can be performed within 72hrs of recieval by refering  laboratory.

Notes

https://handbook.northernpath.org.au/downloads/mandl/Autoimmune-Encephalitis-Testing-Requisition-form-V10-2025.pdf

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

https://handbook.northernpath.org.au/downloads/mandl/MtDNA-Requisition-form-V23-2025.pdf

https://handbook.northernpath.org.au/downloads/mandl/STVMNDL-flyer-with-prices-V17-2025.pdf

https://handbook.northernpath.org.au/downloads/mandl/Specimen-Handling-Autoimmune-Encephalitis-Testing-V9-2025.ppt.pdf

https://handbook.northernpath.org.au/downloads/mandl/Specimen-Handling-Protocol-for-genetic-testing-V21-2025.pdf

Contact Us:

Director of Diagnostic Lab: Professor Steve Collins

Scientists: Dr Rosetta Marotta

Email: rosetta.marotta@svhm.org.au

Ms Judy Chin

Ms Maria Chiotis

Laboratory Hours: 9am – 5pm

Mon-Fri (except public holidays).

No urgent testing unless specified.

Laboratory

Molecular

Immunology

Collection & Request Instructions

Associated with Acquired neuromyotonia and Limbic encephalitis-like syndromes.

 Please include all the provisional, diagnosis or clinical signs.

Test cost $240

For non Northern Health patients the attached billing consent form must be completed

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Associated with Acquired neuromyotonia and Limbic encephalitis-like syndromes.

Please include all the provisional, diagnosis or clinical signs.

Registration Instructions

CSF sample should be directed to Microbiology (NPV) prior to forwarding to refer laboratory.

Test cost $240

Can be ordered in combination with:  NMDA, GABA_B , AMPA, ANTI- LGI 1, ANTI -CASPR2, ANTI- DPPX. (1.0ML csf is adequate for combination testing).

Blood Serum: request for 5.0 mls of blood collected in serum gel (SST).

CSF: request for 1.0mls

Samples not available for delivery following collection are to the department to book in an to be stored at 4 ^oC. Storage at 4 ^o C is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

CSF sample should be directed to Microbiology (NPV) prior to forwarding to refer laboratory.

Test cost $240

For non Northern Health patients the attached billing consent form must be completed:

https://handbook.northernpath.org.au/downloads/mandl/Consent-for-billing-of-tests-V9-2025.pdf

Can be ordered in combination with:  NMDA, GABA_B , AMPA, ANTI- LGI 1, ANTI -CASPR2, ANTI- DPPX. (1.0ML csf is adequate for combination testing).

Blood Serum: request for 5.0 mls of blood collected in serum gel (SST).

CSF: request for 1.0mls

Samples not available for delivery following collection are to the department to book in an to be stored at 4 ^oC. Storage at 4 ^o C is suitable for up to 2 weeks thereafter samples need to be frozen and sent on dry ice.

External Laboratory

Institute of Clin.Pathology & Medical Res. (ICPMR)

Australian Rickettsial Reference Laboratory