Pathology Handbook

Maternal Serum Screening (Sendaway Test)

Alternative Names:

Combined First Trimester Screening (CFTS)
Second Trimester Maternal Serum Screening (2TMSS)
PAPPA-A; free beta hCG
alpha-feto protein; unconjugated estriol; free beta hCG; dimeric inhibin A
Screening for Down syndrome (trisomy 21)
Screening for Edwards syndrome (trisomy 18)
Screening for Patau syndrome (trisomy 13)

Laboratory:

Clinical Biochemistry

Test Code:

MLS

Specimen Types:

Serum

Container Types:

SST

Adults Volume or Mass:

5 mL

Collection & Request Instructions:

Collect at ambient temperature

Combined First Trimester Screening (CFTS) is performed between 9+0 and 13+6 weeks gestation.

Second Trimester Maternal Serum Screening (2TMSS) is performed between 14+0 and 20+6 weeks gestation.

Refer to MSSO-234-MSS-TRF for clinical notes/information required by reference laboratory (VCGS).

Transport Instructions:

Room Temperature